Effect of different platelet?rich fibrin matrices for ridge preservation in multiple tooth extractions: A split?mouth randomized controlled clinical trial

Aim To evaluate dimensional changes in the alveolar ridge and bone structure after tooth extraction when L-PRF or A-PRF+ was used comparison to unassisted socket healing. Materials methods Twenty patients need of at least three extractions aesthetic zone were included. L-PRF, control randomly assigned, leaving one empty socket/edentulous site between conditions. CBCT scans obtained immediately 3 months Horizontal vertical fill calculated. Histological micro-CT analysis biopsies post-surgical structural Results Mean horizontal 1-mm below crest (buccal palatal side) similar for sites (p > 0.05). For fill, (85.2%) (83.8%) showed superior values than (67.9%). The histological radiological reported more newly formed PRF groups, without any significant differences both. Conclusions matrices failed reduce multiple premaxilla. After 3-month healing, both radiographically a superiority fill. Histologically, they seemed accelerate new formation.